Diovan (Novartis, Basel Switzerland) is a drug intended to reduce high blood pressure. Possessing an antihypertensive effect, this medication not only treats negative effects of heart attacks but also helps with stabilizing blood pressure in the case of chronic hypertension.
Form release and dosage
Diovan is available in tablet form. The concentration of the active substance (valsartan) can be either 40 mg, 80 mg, or 160 mg. Initially, a minimum dosage is prescribed, with a gradual increase made if necessary.
The mechanism of action
The agent is intended for oral administration and is rapidly absorbed in the gastrointestinal tract. Through the intestinal mucosa, the active substance penetrates into the blood. The agent acts on a number of receptors, which are found not only in the vessels but also in the kidneys, heart, lungs, or brain. As a consequence, the vessels expand and blood pressure decreases. Moreover, there is a decrease in the increased pulse, which is often observed at high pressure.
Indications for Diovan include the following:
- Persistent increase in blood pressure against the background of the initial stage of hypertension
- Heart failure, which is marked by stagnation with the formation of serious swelling
- Myocardial infarction in the acute phase
Contraindications for Diovan include the following:
- Severe liver diseases
- A severe stage of kidney failure
- Potassium deficiency in the body
- Lack of calcium
- Lack of sodium
It is also impossible to use Diovan in case of individual intolerance.
Mode of application
Tablets are taken regardless of the time of ingestion of food. They are swallowed whole sans crushing or chewing. Diovan should be washed down with water.
According to the instructions for use, the drug prescribed in a daily dosage of 80 mg, which is divided into two receptions of 40 mg. During the recovery from infarction, the dosage of the drug may exceed 320 mg per day.
Potential side effects for Diovan include the following:
- A drop in blood pressure with or without associated dizziness
- Increase in the content of potassium ions
- Pain in the muscles
- Digestive disorders
- Viral infections
- Skin rashes
- Susceptibility to diseases of the upper respiratory tract
- Abdominal pain
- Serum sickness